| TOP LATINO SEMANA 16 – 2010 |
| ES | SA | 2S | 3S | Canción | Artista | SS | PA | Distribuidor |
| 1 | 1 | 2 | 2 | Bad romance | Lady Gaga | 17 | 1(2) | UNIVERSAL |
| 2 | 2 | 1 | 1 | Mientes | Camila | 16 | 1(6) | SONY MUSIC |
| 3 | 3 | 3 | 4 | Tik tok | Ke$ha | 13 | 2 | SONY MUSIC |
| 4 | 5 | 4 | 6 | Me Enamoré de Ti | Chayanne | 19 | 4 | SONY MUSIC |
| 5 | 4 | 5 | 3 | Colgando en tus manos | Carlos Baute & Marta Sánchez | 53 | 1 | WARNER |
| 6 | 16 | RI | 33 | Telephone | Lady Gaga Feat. Beyoncé | 3 | 6 | UNIVERSAL |
| 7 | 7 | 7 | 9 | El doctorado | Tony Dize | 15 | 7 | PINA RECORDS |
| 8 | 9 | 19 | 23 | Gipsy (Gitana) | Shakira | 5 | 8 | SONY MUSIC |
| 9 | 10 | 9 | 10 | Yo no se mañana | Luis Enrique | 34 | 9 | INDEPENDIENTE |
| 10 | 6 | 6 | 5 | Meet me halfway | Black Eyed Peas | 18 | 5 | UNIVERSAL |
| 11 | 8 | 8 | 8 | Desde cuando | Alejandro Sanz | 12 | 8 | WARNER |
| 12 | 21 | NI | | Egoista | Belinda & Pitbull | 2 | 12 | EMI |
| 13 | 14 | 13 | 15 | Dile al amor | Aventura | 11 | 13 | PREMIUM LATIN |
| 14 | 12 | 17 | 19 | Bien o mal | Julieta Venegas | 6 | 12 | SONY MUSIC |
| 15 | 13 | 11 | 12 | Niña bonita | Chino & Nacho Feat. Richie Peña | 41 | 11 | INDEPENDIENTE |
| 16 | 11 | 10 | 13 | Hasta abajo | Don Omar | 12 | 10 | UNIVERSAL |
| 17 | 25 | 23 | NI | Guapa | Diego Torres | 3 | 17 | UNIVERSAL |
| 18 | 24 | 21 | 20 | Te pido perdon | Tito El Bambino | 8 | 16 | UNIVERSAL |
| 19 | 20 | 27 | 25 | Estuve a punto de… | Miguel Bosé | 4 | 19 | WARNER |
| 20 | 22 | 12 | 11 | Se me va la voz | Alejandro Fernandez | 22 | 1(2) | UNIVERSAL |
| 21 | 18 | 20 | 17 | Mi princesa | David Bisbal | 5 | 17 | UNIVERSAL |
| 22 | 27 | 24 | 38 | Pode ir embora | Bruno & Marrone | 4 | 22 | SONY MUSIC |
| 23 | 37 | 25 | RI | Lo que no sabes tu | Chino & Nacho Feat. El Potro Alvares & Baroni | 10 | 23 | UNIVERSAL |
| 24 | 26 | 22 | 22 | Sexy chick (sexy bitch) | David Guetta Feat. Akon | 20 | 9 | UNIVERSAL |
| 25 | 23 | 14 | 14 | Imma be | Black Eyed Peas | 7 | 13 | UNIVERSAL |
| 26 | 30 | 33 | NI | Te siento | Wisin & Yandel | 3 | 26 | UNIVERSAL |
| 27 | 19 | 16 | 18 | Lo hecho esta hecho | Shakira | 21 | 1(2) | SONY MUSIC |
| 28 | 28 | 35 | 29 | Who l am | Nick Jonas & The Administration | 5 | 28 | UNIVERSAL |
| 29 | 15 | NI | | Rebolation | Parangolé | 2 | 15 | ATRACÁO |
| 30 | RI | 39 | NI | Naturally | Selena Gomez | 2 | 30 | HOLLYWOOD RECORDS |
| 31 | 29 | 18 | 7 | Equivocada | Thalía | 22 | 4 | SONY MUSIC |
| 32 | NI | | | Descontrol | Daddy Yankee | 1 | 32 | SONY MUSIC |
| 33 | 33 | 30 | 24 | Fireflies | Owl City | 9 | 24 | UNIVERSAL |
| 34 | RI | 37 | NI | Alice | Avril Lavigne | 2 | 34 | SONY MUSIC |
| 35 | 34 | 32 | 26 | Olvidarte | Pedro Manuel & El Morre Romero | 4 | 26 | SONY MUSIC |
| 36 | 35 | RI | 39 | El run run | Estopa & Rosario | 3 | 35 | SONY MUSIC |
| 37 | 36 | NI | | Detrás de ti | Nelson Arrieta | 2 | 36 | INDEPENDIENTE |
| 38 | 38 | NI | | Waving flag | K´naan & David Bisbal | 2 | 38 | WY RECORDS |
| 39 | 32 | 38 | RI | Más | Nelly Furtado | 8 | 19 | UNIVERSAL |
| 40 | NI | | | Baby | Justin Bieber & Ludacris | 1 | 40 | UNIVERSAL |
| | | | SALIERON | | | | |
| 17 | 15 | 16 | Video phone | Beyoncé & Lady Gaga | 7 | 15 | SONY MUSIC |
| 31 | 28 | 34 | Prummm | Cosculluela Feat. Wisin & Yandel | 4 | 28 | INDEPENDIENTE |
| 39 | RI | | Quiero aprender de ti | El Canto Del Loco | 9 | 18 | SONY MUSIC |
| 40 | 34 | RI | Grito mundial | Dadyy Yankee | 11 | 26 | EL CARTEL RECORDS |
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| | LA GRAN CAÍDA | | 2S | HACE 2 SEMANAS |
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| EL GRAN SALTO | | 3S | HACE 3 SEMANAS |
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| | MAYOR SEMANAS EN LISTA | | SS | SEMANAS EN LISTA |
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| | INGRESO MAS ALTO | | PA | POSICIÓN MAS ALTA |
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| | | RI | REINGRESO | |
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| | | NI | NUEVO INGRESO | |
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