| TOP LATINO SEMANA 40 – 2010 |
| ES | SA | 2S | 3S | Canción | Artista | SS | PA | Distribuidor |
| 1 | 1 | 1 | 1 | Cuando me enamoro | Enrique Iglesias & Juan Luis Guerra | 19 | 1(11) | UNIVERSAL |
| 2 | 2 | 2 | 2 | Aléjate de mi | Camila | 20 | 2(8) | SONY MUSIC |
| 3 | 3 | 3 | 3 | Alejandro | Lady Gaga | 17 | 3(8) | UNIVERSAL |
| 4 | 4 | 5 | 5 | We not speak americano | Yolanda Be Cool | 7 | 4 | INDEPENDIENTE |
| 5 | 5 | 4 | 4 | Yerbatero | Juanes | 12 | 4 | UNIVERSAL |
| 6 | 7 | 7 | 8 | I like it | Enrique Iglesias & Pitbull | 12 | 6 | UNIVERSAL |
| 7 | 21 | NI | Danza kuduro | Don Omar | 2 | 7 | UNIVERSAL |
| 8 | 8 | 8 | 6 | Love the way you lie | Eminem & Rihanna | 7 | 6 | UNIVERSAL |
| 9 | 6 | 6 | 7 | Your love is my drug | Ke$ha | 13 | 6 | SONY MUSIC |
| 10 | 9 | 17 | 9 | Inevitable | Dulce María | 11 | 7 | EMI |
| 11 | 10 | 11 | NI | Club can’t handle me | Florida Ft David Guetta | 3 | 10 | WARNER |
| 12 | 11 | 13 | 11 | All the lovers | Kylie Minogue | 13 | 10 | EMI |
| 13 | 12 | 9 | 10 | California gurls | Katty Perry | 14 | 4 | EMI |
| 14 | 14 | 18 | 16 | Afortunadamente no eres tu | Paty Cantú | 5 | 14 | INDEPENDIENTE |
| 15 | 26 | 33 | 27 | La despedida | Daddy Yankee | 5 | 15 | UNIVERSAL |
| 16 | 17 | 31 | NI | Estoy enamorado | Wisin & Yandel | 3 | 16 | INDEPENDIENTE |
| 17 | 19 | 32 | NI | 24 horas | David Bisbal | 3 | 17 | UNIVERSAL |
| 18 | 25 | 21 | 25 | Mi amor es pobre | Tony Dize Feat. Kem – Y & Arcangel | 6 | 18 | PINA RECORDS |
| 19 | 18 | 40 | NI | Fugidinha | Michel Teló | 3 | 18 | INDEPENDIENTE |
| 20 | 20 | 19 | 17 | El doctorado | Tony Dize | 39 | 4 | PINA RECORDS |
| 21 | 24 | 25 | 30 | Estoy enamorada | Thalia & Pedro Capo | 4 | 21 | SONY MUSIC |
| 22 | 16 | 14 | 15 | Nuestro amor será leyenda | Alejandro Sanz | 13 | 13 | WARNER |
| 23 | 22 | 12 | 14 | Stereo love | Edward Maya Feat. Vika Jigulina Or Alicia | 22 | 10 | CAT MUSIC |
| 24 | 36 | 34 | NI | Somebody to love | Justin Bieber | 5 | 24 | UNIVERSAL |
| 25 | 13 | 10 | 34 | Labios de miel | Luis Miguel | 4 | 10 | WARNER |
| 26 | 15 | 22 | 22 | Soy feliz | Ricardo Montaner | 8 | 15 | EMI |
| 27 | NI | Solo tuyo | Felipe Pelaez | 1 | 27 | SONY MUSIC |
| 28 | NI | Não mais | Victor & Leo | 1 | 28 | SONY MUSIC |
| 29 | 35 | 23 | 38 | El malo | Aventura | 4 | 23 | PREMIUN LATIN MUSIC |
| 30 | 31 | 28 | 31 | Niña bonita | Chino & Nacho Feat. Richie Peña | 65 | 7 | INDEPENDIENTE |
| 31 | 32 | 16 | 13 | Sick of love | Robert Ramirez | 13 | 13 | INDEPENDIENTE |
| 32 | NI | Nada de más | Belanova | 1 | 32 | UNIVERSAL |
| 33 | 27 | 20 | 21 | Gettin’ over you | David Guetta Feat. Chris Willis | 13 | 18 | EMI |
| 34 | 34 | 24 | 23 | Break your heart | Taio Cruz Feat. Ludracris | 17 | 9 | UNIVERSAL |
| 35 | 23 | 29 | 12 | Waka waka (Esto es África) | Shakira | 17 | 1 | SONY MUSIC |
| 36 | 28 | 39 | 26 | Nubes negras | Jean Carlos Centeno | 10 | 18 | SONY MUSIC |
| 37 | 38 | NI | Estar enamorado | Golpe A Golpe | 2 | 37 | INDEPENDIENTE |
| 38 | RI | El bla bla bla | El Potro Alvares Feat. Chino & Nacho | 2 | 38 | INDEPENDIENTE |
| 39 | 29 | 15 | 19 | Como eu queria te amar | Edson | 5 | 15 | EMI |
| 40 | NI | Loca | Shakira ft Dizzie Rascal & El Cata | 1 | 40 | SONY MUSIC |
| | | | SALIERON | | | | |
| 30 | 36 | 33 | Hey soul sister | Train | 11 | 26 | UNIVERSSAL |
| 33 | 26 | 20 | Baby | Justin Bieber & Ludacris | 22 | 3(5) | UNIVERSAL |
| 37 | 27 | RI | Nadie te amará como yo | Dyland & Lenny Feat. Arcangel & Zion | 2 | 23 | SONY MUSIC |
| 39 | RI |
| En todas partes | Hany Kauam | 2 | 36 | INDEPENDIENTE |
| 40 | NI |
| Besos usados | Andrés Cepeda | 1 | 40 | INDEPENDIENTE |
| | | | | | | | |
| | | | LA GRAN CAÍDA | | | 2S | HACE 2 SEMANAS |
| | |
| EL GRAN SALTO | | | 3S | HACE 3 SEMANAS |
| | | | MÁS SEMANAS EN LISTA | | | SS | SEMANAS EN LISTA |
| | | | INGRESO MAS ALTO | | | PA | POSICIÓN MAS ALTA |
| | | | | | | | |
| | | RI | REINGRESO | | | | |
| | | NI | NUEVO INGRESO | | | | |
