| TOP LATINO SEMANA 12 – 2010 |
| ES | SA | 2S | 3S | Canción | Artista | SS | PA | Distribuidor |
| 1 | 1 | 1 | 1 | Mientes | Camila | 12 | 1(4) | SONY MUSIC |
| 2 | 4 | 4 | 4 | Tik tok | Ke$ha | 9 | 2 | SONY MUSIC |
| 3 | 2 | 2 | 3 | Bad romance | Lady Gaga | 13 | 2(2) | UNIVERSAL |
| 4 | 3 | 3 | 2 | Colgando en tus manos | Carlos Baute & Marta Sánchez | 49 | 1 | WARNER |
| 5 | 6 | 6 | 5 | Lo hecho esta hecho | Shakira | 17 | 1(2) | SONY MUSIC |
| 6 | 5 | 5 | 14 | Me Enamoré de Ti | Chayanne | 15 | 5 | SONY MUSIC |
| 7 | 9 | 9 | 8 | Meet me halfway | Black Eyed Peas | 14 | 7 | UNIVERSAL |
| 8 | 13 | 18 | 22 | El doctorado | Tony Dize | 11 | 8 | PINA RECORDS |
| 9 | 10 | 12 | 13 | Desde cuando | Alejandro Sanz | 8 | 9 | WARNER |
| 10 | 11 | 10 | 10 | Yo no se mañana | Luis Enrique | 30 | 10 | INDEPENDIENTE |
| 11 | 17 | 13 | 18 | Hasta abajo | Don Omar | 8 | 11 | UNIVERSAL |
| 12 | 16 | 17 | 17 | Niña bonita | Chino & Nacho Feat. Richie Peña | 37 | 12 | INDEPENDIENTE |
| 13 | 15 | 21 | NI | Imma be | Black Eyed Peas | 3 | 13 | UNIVERSAL |
| 14 | 14 | 15 | 15 | Dile al amor | Aventura | 7 | 14 | PREMIUM LATIN |
| 15 | 12 | 11 | 6 | Russian roulette | Rihanna | 11 | 6 | UNIVERSAL |
| 16 | 23 | 22 | 23 | Te pido perdon | Tito El Bambino | 4 | 16 | UNIVERSAL |
| 17 | 7 | 7 | 7 | Equivocada | Thalía | 18 | 4 | SONY MUSIC |
| 18 | 8 | 8 | 9 | Se me va la voz | Alejandro Fernandez | 18 | 1(2) | UNIVERSAL |
| 19 | 24 | 34 | NI | Mi princesa | David Bisbal | 3 | 19 | UNIVERSAL |
| 20 | 20 | 14 | 16 | Sexy chick (sexy bitch) | David Guetta Feat. Akon | 16 | 9 | UNIVERSAL |
| 21 | 29 | NI | | Bien o mal | Julieta Venegas | 2 | 21 | SONY MUSIC |
| 22 | 18 | 28 | 40 | Video phone | Beyoncé & Lady Gaga | 4 | 18 | SONY MUSIC |
| 23 | 28 | RI | 19 | I Know you want me (Calle Ocho) | Pitbull | 39 | 2(2) | UNIVERSAL |
| 24 | 27 | 35 | 30 | Lo que no sabes tu | Chino & Nacho Feat. El Potro Alvares & Baroni | 7 | 24 | UNIVERSAL |
| 25 | 21 | 23 | 33 | Verano Azul | Juan Magan | 7 | 21 | UNIVERSAL |
| 26 | 31 | 40 | RI | Fireflies | Owl City | 5 | 26 | UNIVERSAL |
| 27 | 39 | 26 | 28 | Quiero aprender de ti | El Canto Del Loco | 8 | 18 | SONY MUSIC |
| 28 | 25 | 25 | 24 | Atrévete a quererme | Nelson Velásquez | 6 | 24 | SONY MUSIC |
| 29 | NI |
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| Enseñame a quererte | Angel Laez | 1 | 29 | INDEPENDIENTE |
| 30 | NI |
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| Fã | Christian & Cristiano | 1 | 28 | INDEPENDIENTE |
| 31 | 22 | 16 | 11 | Looking for paradise | Alejandro Sanz & Alicia Keys | 22 | 1(5) | WARNER |
| 32 | 36 | 38 | 34 | I gotta feeling | Black Eyed Peas | 37 | 2 | UNIVERSAL |
| 33 | 19 | 20 | 26 | Más | Nelly Furtado | 5 | 19 | UNIVERSAL |
| 34 | 38 | 36 | 32 | Ni rosas ni juguetes | Paulina Rubio | 25 | 5 | UNIVERSAL |
| 35 | NI |
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| Who l am | Nick Jonas & The Administration | 1 | 35 | UNIVERSAL |
| 36 | 30 | 27 | 27 | Mi delirio | Anahí | 6 | 27 | EMI |
| 37 | RI | 32 | 37 | Chocolate | Jesse & Joy | 3 | 32 | WARNER |
| 38 | NI |
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| Prummm | Cosculluela Feat. Wisin & Yandel | 1 | 38 | INDEPENDIENTE |
| 39 | 26 | 24 | 12 | Gracias a ti | Wisin & Yandel | 25 | 4 | UNIVERSAL |
| 40 | NI |
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| Gipsy (Gitana) | Shakira | 1 | 40 | SONY MUSIC |
| | | | SALIERON | | | | |
| 32 | 29 | 35 | Te perdone | Jorge Celedon | 12 | 25 | SONY MUSIC |
| 33 | 30 | NI | Sueño contigo | Tecupae & Cabas | 2 | 30 | INDEPENDIENTE |
| 34 | 19 | 21 | As máscaras | Claudia Leitte | 6 | 19 | UNIVERSAL |
| 35 | 37 | 31 | Se apagó la llama | Chino & Nacho Feat. Rakim & Kem Y | 16 | 12 | UNIVERSAL |
| 37 | 33 | NI | Empire state of mind | Jay Z & Alicia Keys | 2 | 33 | UNIVERSAL |
| 40 | RI | | You know me | Robbie Williams | 3 | 35 | EMI |
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| | LA GRAN CAÍDA | | 2S | HACE 2 SEMANAS |
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| EL GRAN SALTO | | 3S | HACE 3 SEMANAS |
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| | MAYOR SEMANAS EN LISTA | | SS | SEMANAS EN LISTA |
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| | INGRESO MAS ALTO | | PA | POSICIÓN MAS ALTA |
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| | | RI | REINGRESO | |
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| | | NI | NUEVO INGRESO | |
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