| TOP LATINO SEMANA 10 – 2010 |
| ES | SA | 2S | 3S | Canción | Artista | SS | PA | Distribuidor |
| 1 | 1 | 4 | 6 | Mientes | Camila | 10 | 1(2) | SONY MUSIC |
| 2 | 3 | 3 | 4 | Bad romance | Lady Gaga | 11 | 2 | UNIVERSAL |
| 3 | 2 | 1 | 2 | Colgando en tus manos | Carlos Baute & Marta Sánchez | 47 | 1 | WARNER |
| 4 | 4 | 5 | 5 | Tik tok | Ke$ha | 7 | 4 | SONY MUSIC |
| 5 | 14 | 13 | 11 | Me Enamoré de Ti | Chayanne | 13 | 5 | SONY MUSIC |
| 6 | 5 | 2 | 1 | Lo hecho esta hecho | Shakira | 15 | 1(2) | SONY MUSIC |
| 7 | 7 | 8 | 7 | Equivocada | Thalía | 16 | 4 | SONY MUSIC |
| 8 | 9 | 6 | 3 | Se me va la voz | Alejandro Fernandez | 16 | 1(2) | UNIVERSAL |
| 9 | 8 | 12 | 12 | Meet me halfway | Black Eyed Peas | 12 | 8 | UNIVERSAL |
| 10 | 10 | 11 | 10 | Yo no se mañana | Luis Enrique | 28 | 10 | INDEPENDIENTE |
| 11 | 6 | 7 | 9 | Russian roulette | Rihanna | 9 | 6 | UNIVERSAL |
| 12 | 13 | 18 | 22 | Desde cuando | Alejandro Sanz | 6 | 12 | WARNER |
| 13 | 18 | 21 | 27 | Hasta abajo | Don Omar | 6 | 13 | UNIVERSAL |
| 14 | 16 | 22 | 16 | Sexy chick (sexy bitch) | David Guetta Feat. Akon | 14 | 9 | UNIVERSAL |
| 15 | 15 | 15 | 21 | Dile al amor | Aventura | 5 | 15 | PREMIUM LATIN |
| 16 | 11 | 9 | 8 | Looking for paradise | Alejandro Sanz & Alicia Keys | 20 | 1(5) | WARNER |
| 17 | 17 | 20 | 17 | Niña bonita | Chino & Nacho Feat. Richie Peña | 35 | 12 | INDEPENDIENTE |
| 18 | 22 | 23 | 23 | El doctorado | Tony Dize | 9 | 18 | PINA RECORDS |
| 19 | 21 | 25 | 26 | As máscaras | Claudia Leitte | 5 | 19 | UNIVERSAL |
| 20 | 26 | 26 | NI | Más | Nelly Furtado | 3 | 20 | UNIVERSAL |
| 21 | NI |
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| Imma be | Black Eyed Peas | 1 | 21 | UNIVERSAL |
| 22 | 23 | NI | | Te pido perdon | Tito El Bambino | 2 | 22 | UNIVERSAL |
| 23 | 33 | 31 | RI | Verano Azul | Juan Magan | 5 | 23 | UNIVERSAL |
| 24 | 12 | 10 | 13 | Gracias a ti | Wisin & Yandel | 23 | 4 | UNIVERSAL |
| 25 | 24 | 24 | 33 | Atrévete a quererme | Nelson Velásquez | 4 | 24 | SONY MUSIC |
| 26 | 28 | 19 | 18 | Quiero aprender de ti | El Canto Del Loco | 6 | 18 | SONY MUSIC |
| 27 | 27 | 27 | 32 | Mi delirio | Anahí | 4 | 27 | EMI |
| 28 | 40 | NI | | Video phone | Beyoncé & Lady Gaga | 2 | 28 | SONY MUSIC |
| 29 | 35 | 34 | 25 | Te perdone | Jorge Celedon | 11 | 25 | SONY MUSIC |
| 30 | NI |
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| Sueño contigo | Tecupae & Cabas | 1 | 30 | INDEPENDIENTE |
| 31 | 25 | 36 | RI | Ego | Beyoncé | 6 | 20 | SONY MUSIC |
| 32 | 37 | NI | | Chocolate | Jesse & Joy | 2 | 32 | WARNER |
| 33 | NI |
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| Empire state of mind | Jay-Z & Alicia Keys | 1 | 33 | UNIVERSAL |
| 34 | NI |
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| Mi princesa | David Bisbal | 1 | 34 | UNIVERSAL |
| 35 | 30 | 28 | 31 | Lo que no sabes tu | Chino & Nacho Feat. El Potro Alvares & Baroni | 5 | 28 | UNIVERSAL |
| 36 | 32 | 17 | 19 | Ni rosas ni juguetes | Paulina Rubio | 23 | 5 | UNIVERSAL |
| 37 | 31 | RI | 30 | Se apagó la llama | Chino & Nacho Feat. Rakim & Kem Y | 15 | 12 | UNIVERSAL |
| 38 | 34 | 30 | 28 | I gotta feeling | Black Eyed Peas | 35 | 2 | UNIVERSAL |
| 39 | 29 | 32 | RI | Su veneno | Aventura | 11 | 17 | PREMIUM LATIN |
| 40 | RI | 33 | 37 | Fireflies | Owl City | 3 | 33 | UNIVERSAL |
| | | | SALIERON | | | | |
| 19 | 16 | 15 | I Know you want me (Calle Ocho) | Pitbull | 37 | 2(2) | UNIVERSAL |
| 20 | 14 | 14 | Esclavo de sus besos | David Bisbal | 23 | 1(2) | UNIVERSAL |
| 36 | NI | | Besala | Mulato | 1 | 36 | INDEPENDIENTE |
| 38 | 37 | 36 | 3 | Britney Spears | 17 | 10 | SONY MUSIC |
| 39 | 38 | RI | Grito mundial | Dadyy Yankee | 9 | 26 | EL CARTEL RECORDS |
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| | ESTRENO MUNDIAL | | | | |
| | | | Amiga | Demphra | | | PANAMA MUSIC |
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| | LA GRAN CAÍDA | | 2S | HACE 2 SEMANAS |
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| EL GRAN SALTO | | 3S | HACE 3 SEMANAS |
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| | MAYOR SEMANAS EN LISTA | | SS | SEMANAS EN LISTA |
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| | INGRESO MAS ALTO | | PA | POSICIÓN MAS ALTA |
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| | | RI | REINGRESO | | |
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| | | NI | NUEVO INGRESO | | |
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