| TOP LATINO SEMANA 41 – 2010 |
| ES | SA | 2S | 3S | Canción | Artista | SS | PA | Distribuidor |
| 1 | 1 | 1 | 1 | Cuando me enamoro | Enrique Iglesias & Juan Luis Guerra | 20 | 1(12) | UNIVERSAL |
| 2 | 2 | 2 | 2 | Aléjate de mi | Camila | 21 | 2(9) | SONY MUSIC |
| 3 | 4 | 4 | 5 | We not speak americano | Yolanda Be Cool | 8 | 3 | INDEPENDIENTE |
| 4 | 3 | 3 | 3 | Alejandro | Lady Gaga | 18 | 3(8) | UNIVERSAL |
| 5 | 5 | 5 | 4 | Yerbatero | Juanes | 13 | 4 | UNIVERSAL |
| 6 | 7 | 21 | NI | Danza kuduro | Don Omar | 3 | 6 | UNIVERSAL |
| 7 | 6 | 7 | 7 | I like it | Enrique Iglesias & Pitbull | 13 | 7 | UNIVERSAL |
| 8 | 10 | 9 | 17 | Inevitable | Dulce María | 12 | 7 | EMI |
| 9 | 11 | 10 | 11 | Club can’t handle me | Florida Ft David Guetta | 4 | 9 | WARNER |
| 10 | 8 | 8 | 8 | Love the way you lie | Eminem & Rihanna | 8 | 6 | UNIVERSAL |
| 11 | 9 | 6 | 6 | Your love is my drug | Ke$ha | 14 | 6 | SONY MUSIC |
| 12 | 16 | 17 | 31 | Estoy enamorado | Wisin & Yandel | 4 | 12 | INDEPENDIENTE |
| 13 | NI | Teenage dream | Katty Perry | 1 | 13 | EMI |
| 14 | 15 | 26 | 33 | La despedida | Daddy Yankee | 6 | 15 | UNIVERSAL |
| 15 | 13 | 12 | 9 | California gurls | Katty Perry | 15 | 4 | EMI |
| 16 | 19 | 18 | 40 | Fugidinha | Michel Teló | 4 | 16 | INDEPENDIENTE |
| 17 | 18 | 25 | 21 | Mi amor es pobre | Tony Dize Feat. Kem – Y & Arcangel | 7 | 17 | PINA RECORDS |
| 18 | 17 | 19 | 32 | 24 horas | David Bisbal | 4 | 17 | UNIVERSAL |
| 19 | 14 | 14 | 18 | Afortunadamente no eres tu | Paty Cantú | 6 | 14 | INDEPENDIENTE |
| 20 | 28 | NI | Não mais | Victor & Leo | 2 | 20 | SONY MUSIC |
| 21 | 22 | 16 | 14 | Nuestro amor será leyenda | Alejandro Sanz | 14 | 13 | WARNER |
| 22 | 21 | 24 | 25 | Estoy enamorada | Thalia & Pedro Capo | 5 | 21 | SONY MUSIC |
| 23 | 23 | 22 | 12 | Stereo love | Edward Maya Feat. Vika Jigulina Or Alicia | 23 | 10 | CAT MUSIC |
| 24 | 24 | 36 | 34 | Somebody to love | Justin Bieber | 6 | 24 | UNIVERSAL |
| 25 | 20 | 20 | 19 | El doctorado | Tony Dize | 40 | 4 | PINA RECORDS |
| 26 | 25 | 13 | 10 | Labios de miel | Luis Miguel | 5 | 10 | WARNER |
| 27 | 40 | NI | Loca | Shakira ft Dizzie Rascal & El Cata | 2 | 27 | SONY MUSIC |
| 28 | 31 | 32 | 16 | Sick of love | Robert Ramirez | 14 | 13 | INDEPENDIENTE |
| 29 | 36 | 28 | 39 | Nubes negras | Jean Carlos Centeno | 11 | 18 | SONY MUSIC |
| 30 | 26 | 15 | 22 | Soy feliz | Ricardo Montaner | 9 | 15 | EMI |
| 31 | NI | Estar contigo | Alex Ubago – Jorge Villamizar & Lena | 1 | 31 | WARNER |
| 32 | 12 | 11 | 13 | All the lovers | Kylie Minogue | 14 | 10 | EMI |
| 33 | 37 | 38 | NI | Estar enamorado | Golpe A Golpe | 3 | 33 | INDEPENDIENTE |
| 34 | NI | Never say never | Justin Bieber & Jaden Smith | 1 | 34 | UNIVERSAL |
| 35 | 34 | 34 | 24 | Break your heart | Taio Cruz Feat. Ludracris | 18 | 9 | UNIVERSAL |
| 36 | 33 | 27 | 20 | Gettin’ over you | David Guetta Feat. Chris Willis | 14 | 18 | EMI |
| 37 | NI | Mi corazón se fue | Diego Torres | 1 | 37 | UNIVERSAL |
| 38 | 27 | NI | Solo tuyo | Felipe Pelaez | 2 | 27 | SONY MUSIC |
| 39 | 38 | RI | El bla bla bla | El Potro Alvares Feat. Chino & Nacho | 3 | 38 | INDEPENDIENTE |
| 40 | NI | Dynamite | Taio Cruz | 1 | 40 | UNIVERSAL |
| | | | SALIERON | | | | |
| 29 | 35 | 23 | El malo | Aventura | 4 | 23 | PREMIUN LATIN MUSIC |
| 30 | 31 | 28 | Niña bonita | Chino & Nacho Feat. Richie Peña | 65 | 7 | INDEPENDIENTE |
| 32 | NI | | Nada de más | Belanova | 1 | 32 | UNIVERSAL |
| 35 | 23 | 29 | Waka waka (Esto es África) | Shakira | 17 | 1 | SONY MUSIC |
| 39 | 29 | 15 | Como eu queria te amar | Edson | 5 | 15 | EMI |
| | | | | | | | |
| | | | LA GRAN CAÍDA | | | 2S | HACE 2 SEMANAS |
| | |
| EL GRAN SALTO | | | 3S | HACE 3 SEMANAS |
| | | | MÁS SEMANAS EN LISTA | | | SS | SEMANAS EN LISTA |
| | | | INGRESO MAS ALTO | | | PA | POSICIÓN MAS ALTA |
| | | | | | | | |
| | | RI | REINGRESO | | | | |
| | | NI | NUEVO INGRESO | | | | |
