| TOP LATINO SEMANA 45 – 2010 |
| ES | SA | 2S | 3S | Canción | Artista | SS | PA | Distribuidor |
| 1 | 3 | 5 | 12 | Loca | Shakira ft Dizzie Rascal & El Cata | 6 | 1 | SONY MUSIC |
| 2 | 5 | 3 | 5 | Danza kuduro | Don Omar | 7 | 2 | UNIVERSAL |
| 3 | 4 | 2 | 2 | We not speak americano | Yolanda Be Cool | 12 | 2(2) | INDEPENDIENTE |
| 4 | 1 | 1 | 1 | Cuando me enamoro | Enrique Iglesias & Juan Luis Guerra | 24 | 1(15) | UNIVERSAL |
| 5 | 8 | 9 | 6 | Love the way you lie | Eminem & Rihanna | 12 | 5 | UNIVERSAL |
| 6 | 10 | 8 | 10 | Teenage dream | Katty Perry | 5 | 6 | EMI |
| 7 | 6 | 7 | 9 | I like it | Enrique Iglesias & Pitbull | 17 | 6 | UNIVERSAL |
| 8 | 7 | 10 | 8 | Club can’t handle me | Florida Ft David Guetta | 8 | 7 | WARNER |
| 9 | 13 | NI | | Besame | Camila | 2 | 9 | SONY MUSIC |
| 10 | 2 | 4 | 4 | Alejandro | Lady Gaga | 22 | 2 | UNIVERSAL |
| 11 | 9 | 11 | 11 | Somebody to love | Justin Bieber | 10 | 9 | UNIVERSAL |
| 12 | 11 | 22 | NI | Dj got us fallin in love | Usher Feat. Pitbull | 3 | 11 | SONY MUSIC |
| 13 | 16 | 13 | 13 | Estoy enamorado | Wisin & Yandel | 8 | 12 | INDEPENDIENTE |
| 14 | 14 | 21 | NI | Prohibido quererme | Ov7 | 3 | 14 | SONY MUSIC |
| 15 | 15 | 14 | 14 | La despedida | Daddy Yankee | 10 | 14 | UNIVERSAL |
| 16 | 12 | 6 | 3 | Aléjate de mi | Camila | 25 | 2(9) | SONY MUSIC |
| 17 | 17 | 23 | 30 | Dynamite | Taio Cruz | 5 | 17 | UNIVERSAL |
| 18 | 23 | NI | | Corazon sin cara | Prince Royce | 2 | 18 | TOP STOP |
| 19 | 21 | 24 | 28 | Solo tuyo | Felipe Pelaez | 6 | 19 | SONY MUSIC |
| 20 | NI | Adrenalina | Luan Santana | 1 | 20 | SONY MUSIC |
| 21 | 19 | 18 | 17 | Estoy enamorada | Thalia & Pedro Capo | 9 | 17 | SONY MUSIC |
| 22 | 20 | 15 | 34 | Estar contigo | Alex Ubago – Jorge Villamizar & Lena | 5 | 15 | WARNER |
| 23 | 24 | 27 | 35 | Mi corazón se fue | Diego Torres | 5 | 23 | UNIVERSAL |
| 24 | 18 | 12 | 7 | Yerbatero | Juanes | 17 | 4 | UNIVERSAL |
| 25 | RI | 16 | NI | Tu voz | Erik Rubin | 2 | 16 | INDEPENDIENTE |
| 26 | RI | Pensando en ti | M.Pizzolante, Servando & Florentino | 1 | 26 | INDEPENDIENTE |
| 27 | RI | Si no le contesto | Plan B | 1 | 27 | PINA RECORDS |
| 28 | RI | Nada de más | Belanova | 2 | 28 | UNIVERSAL |
| 29 | 26 | 30 | 25 | Stereo love | Edward Maya Feat. Vika Jigulina Or Alicia | 27 | 10 | CAT MUSIC |
| 30 | 39 | RI | Tu angelito | Chino & Nacho | 4 | 30 | UNIVERSAL |
| 31 | NI | Only girl | Rihanna | 1 | 31 | UNIVERSAL |
| 32 | 30 | 31 | 33 | El malo | Aventura | 8 | 23 | PREMIUN LATIN MUSIC |
| 33 | NI | Just the way you are | Bruno Mars | 1 | 33 | WARNER |
| 34 | 28 | 19 | 23 | Labios de miel | Luis Miguel | 9 | 10 | WARNER |
| 35 | 32 | 32 | 38 | Y si te quedas que | Santiago Cruz | 4 | 32 | INDEPENDIENTE |
| 36 | NI | Quiere pa’ que te quieran | Dyland & Lenny | 1 | 36 | SONY MUSIC |
| 37 | 22 | 17 | 18 | California gurls | Katty Perry | 19 | 4 | EMI |
| 38 | 31 | 33 | 32 | 24 horas | David Bisbal | 8 | 17 | UNIVERSAL |
| 39 | 35 | 26 | 21 | Nuestro amor será leyenda | Alejandro Sanz | 18 | 13 | WARNER |
| 40 | 27 | NI | 16 añitos | Dani Martin | 2 | 27 | SONY MUSIC |
| | | | SALIERON | | | | |
| 25 | 25 | 29 | Fugidinha | Michel Teló | 7 | 16 | INDEPENDIENTE |
| 29 | 34 | 26 | Mi amor es pobre | Tony Dize Feat. Kem – Y & Arcangel | 10 | 17 | PINA RECORDS |
| 33 | 35 | NI | Se acabo el amor | Los Adolescentes | 2 | 33 | INDEPENDIENTE |
| 34 | NI | | Me gustas | Tecupae & Peter Manjarres | 1 | 34 | INDEPENDIENTE |
| 36 | RI | 37 | Estar enamorado | Golpe A Golpe | 5 | 33 | INDEPENDIENTE |
| 37 | 40 | NI | La gua gua | Juan Luis Guerra | 2 | 37 | CAPITOL LATIN |
| 38 | 39 | 20 | All the lovers | Kylie Minogue | 17 | 10 | EMI |
| 40 | NI | | Billonaire | Travie McCoy & Bruno Mars | 1 | 40 | INDEPENDIENTE |
| | | | | | | | |
| | | | LA GRAN CAÍDA | | 2S | HACE 2 SEMANAS |
| | |
| EL GRAN SALTO | | 3S | HACE 3 SEMANAS |
| | | | MÁS SEMANAS EN LISTA | | SS | SEMANAS EN LISTA |
| | | | INGRESO MAS ALTO | | PA | POSICIÓN MAS ALTA |
| | | | | | | | |
| | | RI | REINGRESO | | |
| |
| | | NI | NUEVO INGRESO | | |
| |
