| TOP LATINO SEMANA 49 – 2010 |
| ES | SA | 2S | 3S | Canción | Artista | SS | PA | Distribuidor |
| 1 | 1 | 1 | 1 | Loca | Shakira ft Dizzie Rascal & El Cata | 10 | 1(5) | SONY MUSIC |
| 2 | 2 | 2 | 5 | Danza kuduro | Don Omar | 11 | 2(3) | UNIVERSAL |
| 3 | 3 | 9 | 25 | Only girl | Rihanna | 5 | 3(2) | UNIVERSAL |
| 4 | 6 | 6 | 9 | Bésame | Camila | 6 | 4 | SONY MUSIC |
| 5 | 12 | 12 | 10 | Estoy enamorado | Wisin & Yandel | 12 | 5 | INDEPENDIENTE |
| 6 | 9 | 7 | 3 | Cuando me enamoro | Enrique Iglesias & Juan Luis Guerra | 28 | 1(15) | UNIVERSAL |
| 7 | 14 | 20 | 22 | Just the way you are | Bruno Mars | 5 | 7 | WARNER |
| 8 | 13 | 10 | 13 | La despedida | Daddy Yankee | 14 | 8 | UNIVERSAL |
| 9 | 7 | 8 | 8 | Club can’t handle me | Florida Ft David Guetta | 12 | 7 | WARNER |
| 10 | 26 | 13 | 11 | Dj got us fallin in love | Usher Feat. Pitbull | 7 | 10 | SONY MUSIC |
| 11 | 17 | 15 | 12 | I like it | Enrique Iglesias & Pitbull | 21 | 6 | UNIVERSAL |
| 12 | 4 | 3 | 4 | We not speak americano | Yolanda Be Cool | 16 | 2(2) | INDEPENDIENTE |
| 13 | 5 | 4 | 2 | Love the way you lie | Eminem & Rihanna | 16 | 2 | UNIVERSAL |
| 14 | 22 | 16 | 19 | Nada de más | Belanova | 6 | 14 | UNIVERSAL |
| 15 | 10 | 11 | 14 | Prohibido quererme | Ov7 | 7 | 10 | SONY MUSIC |
| 16 | 19 | 34 | 38 | Y no regresas | Juanes | 4 | 16 | UNIVERSAL |
| 17 | 11 | 23 | 6 | Alejandro | Lady Gaga | 26 | 2 | UNIVERSAL |
| 18 | 16 | 14 | 7 | Teenage dream | Katty Perry | 9 | 6 | EMI |
| 19 | 18 | 26 | 30 | Tu angelito | Chino & Nacho | 8 | 18 | UNIVERSAL |
| 20 | 15 | 18 | 17 | Dynamite | Taio Cruz | 9 | 15 | UNIVERSAL |
| 21 | 8 | 5 | 21 | Estar contigo | Alex Ubago – Jorge Villamizar & Lena | 9 | 5 | WARNER |
| 22 | 20 | 24 | 20 | Solo tuyo | Felipe Pelaez | 10 | 19 | SONY MUSIC |
| 23 | 30 | NI | Pra você lembrar | Restart | 2 | 23 | RADAR |
| 24 | 28 | 29 | 35 | Si no le contesto | Plan B | 5 | 27 | PINA RECORDS |
| 25 | 25 | 19 | 18 | Estoy enamorada | Thalia & Pedro Capo | 13 | 17 | SONY MUSIC |
| 26 | 35 | 37 | NI | Bon bon | Pitbull | 3 | 26 | SONY MUSIC |
| 27 | 29 | 25 | 15 | Somebody to love | Justin Bieber | 14 | 9 | UNIVERSAL |
| 28 | 23 | 17 | 16 | Adrenalina | Luan Santana | 5 | 16 | SONY MUSIC |
| 29 | 21 | 22 | 24 | Corazon sin cara | Prince Royce | 6 | 18 | TOP STOP |
| 30 | 27 | 27 | 28 | Y si te quedas que | Santiago Cruz | 8 | 27 | INDEPENDIENTE |
| 31 | 24 | 21 | 23 | Aléjate de mi | Camila | 29 | 2(9) | SONY MUSIC |
| 32 | RI | 34 | Labios de miel | Luis Miguel | 11 | 10 | WARNER |
| 33 | NI | Se me apaga la vida | Los Pelaos | 1 | 33 | RHIT |
| 34 | NI | La ocasión para amarnos | Maria José | 1 | 34 | INDEPENDIENTE |
| 35 | NI | Lo mejor de mi vida eres tu | Ricky Martin | 1 | 35 | SONY MUSIC |
| 36 | 37 | 33 | 31 | Stereo love | Edward Maya Feat. Vika Jigulina Or Alicia | 31 | 10 | CAT MUSIC |
| 37 | 39 | RI | Inevitable | Dulce María | 16 | 7 | EMI |
| 38 | NI | La calle | Juan Luis Guerra & Juanes | 1 | 38 | UNIVERSAL |
| 39 | NI | A donde vamos a parar | Marco Antonio Solis | 1 | 39 | INDEPENDIENTE |
| 40 | NI | The time | Black Eyed Peas | 1 | 40 | UNIVERSAL |
| | | | SALIERON | | | | |
| 31 | 32 | 29 | Mi corazón se fue | Diego Torres | 8 | 23 | UNIVERSAL |
| 32 | 28 | 26 | El malo | Aventura | 11 | 23 | PREMIUN LATIN MUSIC |
| 33 | NI | | Tu | Omar Enrique e Ilegales | 1 | 33 | GMS |
| 34 | NI | | La persona de mi vida | Ivan Villazon | 1 | 34 | INDEPENDIENTE |
| 36 | 35 | 32 | Quiere pa’ que te quieran | Dyland & Lenny | 4 | 32 | SONY MUSIC |
| 38 | 40 | RI | Billonaire | Travie McCoy & Bruno Mars | 2 | 38 | INDEPENDIENTE |
| 40 | 31 | 27 | Yerbatero | Juanes | 20 | 4 | UNIVERSAL |
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| | | | LA GRAN CAÍDA | | 2S | HACE 2 SEMANAS |
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| EL GRAN SALTO | | 3S | HACE 3 SEMANAS |
| | | | MÁS SEMANAS EN LISTA | | SS | SEMANAS EN LISTA |
| | | | INGRESO MAS ALTO | | PA | POSICIÓN MAS ALTA |
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| | | RI | REINGRESO | | |
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| | | NI | NUEVO INGRESO | | |
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